SCHEMBL7846261

SCHEMBL7846261

[c]1ncc(C2CCCCCCC2)[nH]1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.37
NPY5R Q15761 1/20 0.35
CYP11B2 P19099 1/20 0.33
TDO2 P48775 1/20 0.32
GCGR P47871 1/20 0.32
MAPK14 Q16539 1/20 0.32
CSF1R P07333 1/20 0.32
NISCH Q9Y2I1 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7854908 1.00 DAO (0.37) DAONPY5RCYP11B2TDO2GCGR
SCHEMBL7853188 1.00 DAO (0.37) DAONPY5RCYP11B2TDO2GCGR
SCHEMBL7845712 0.98 DAO (0.35) DAONPY5RCYP11B2TDO2HCAR2
SCHEMBL7854665 0.94
SCHEMBL7854141 0.68 DAO (0.38) DAONPY5RCYP11B2CSF1RNISCH
SCHEMBL7843969 0.68 DAO (0.38) DAONPY5RCYP11B2CSF1RNISCH
SCHEMBL7845292 0.68 DAO (0.38) DAONPY5RCYP11B2CSF1RNISCH
SCHEMBL7852604 0.65 DAO (0.36) DAONPY5RCSF1RALDH1A1HCAR2
SCHEMBL31314522 0.62 DAO (0.45) DAONPY5RCYP11B2GCGRMAPK14
SCHEMBL17571954 0.61 NPY5R (0.47) DAONPY5RCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719258-B1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMA CO LTD (JP) 2001-10-31 EP disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0719258-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-07-03 EP disclosed
WO-1996002508-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-02-01 WO disclosed