Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 11/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846816 | 1.00 | KCNH2 (0.44) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8181676 | 0.85 | KCNH2 (0.51) | KCNH2POLBCYP3A4KDM4EPRKD3 | |
| SCHEMBL7836068 | 0.85 | KCNH2 (0.51) | KCNH2POLBCYP3A4KDM4EPRKD3 | |
| SCHEMBL7844795 | 0.84 | GSK3B (0.45) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL7835094 | 0.83 | CACNA1F (0.60) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL7835088 | 0.83 | CACNA1F (0.60) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL5783269 | 0.80 | GSK3B (0.51) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL502617 | 0.80 | GSK3B (0.51) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL4747701 | 0.78 | GSK3B (0.49) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8181763 | 0.76 | KCNH2 (0.60) | KCNH2POLBGSK3BKDM4EPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911336-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-6017911-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0911336-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-04-28 | — | — | EP | disclosed |