Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499135 | 1.00 | PTPN1 (0.85) | PTPN1 | |
| SCHEMBL7497921 | 0.92 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7503222 | 0.82 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL8473653 | 0.82 | PTPN1 (0.64) | PTPN1 | |
| SCHEMBL8473658 | 0.82 | PTPN1 (0.64) | PTPN1 | |
| SCHEMBL7504200 | 0.79 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7499892 | 0.79 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7837224 | 0.76 | PTPN1 (0.62) | PTPN1 | |
| SCHEMBL7506764 | 0.75 | PTPN1 (0.69) | PTPN1 | |
| SCHEMBL7506784 | 0.74 | PTPN1 (1.00) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077967-A2 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058518-A2 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |