Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841749 | 0.97 | EGFR (0.44) | EGFRKDRERBB2 | |
| SCHEMBL7847974 | 0.87 | EGFR (0.45) | EGFRKDRERBB2 | |
| SCHEMBL1384673 | 0.80 | EGFR (0.70) | EGFRKDRERBB2 | |
| SCHEMBL1383950 | 0.80 | EGFR (0.70) | EGFRKDRERBB2 | |
| SCHEMBL4220580 | 0.79 | EGFR (0.57) | EGFRKDRERBB2 | |
| SCHEMBL4225530 | 0.79 | EGFR (0.57) | EGFRKDRERBB2 | |
| SCHEMBL4226627 | 0.79 | EGFR (0.57) | EGFRKDRERBB2 | |
| SCHEMBL1386754 | 0.79 | EGFR (0.57) | EGFRKDRERBB2 | |
| SCHEMBL6989473 | 0.77 | EGFR (0.58) | EGFRKDRERBB2 | |
| SCHEMBL6995705 | 0.76 | EGFR (0.57) | EGFRKDRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163227-A1 | BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, AND PROCESSES FOR PREPARING THEM | Boehringer Ingelheim Pharma KG (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055141-A1 | BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, AND PROCESSES FOR PREPARING THEM | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-21 | — | — | WO | disclosed |