Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7849649 | 0.98 | CA1 (0.65) | CA1CA2CA12CA9MMP1 | |
| Water SCHEMBL8887158 | 0.96 | CA1 (0.67) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL1102016 | 0.94 | CA1 (0.69) | CA1CA2CA12CA9MMP1 | |
| Water SCHEMBL7847594 | 0.93 | CA1 (0.62) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL28226036 | 0.92 | CA1 (0.67) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL27468362 | 0.92 | CA1 (0.67) | CA1CA2CA12CA9MMP1 | |
| Hydrochloric Acid SCHEMBL4590542 | 0.92 | CA1 (0.67) | CA1CA2CA12CA9MMP1 | |
| Carbimide SCHEMBL28250589 | 0.87 | CA1 (0.61) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL11755173 | 0.84 | CA1 (0.57) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL2084998 | 0.84 | CA1 (0.57) | CA1CA2CA12CA9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218088-B1 | RADIATION TRANSPARENT SUPPORT, PHOTOSENSITIVE MULTILAYER | FUJI PHOTO FILM CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |