⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22406239 | 0.83 | CDC25B (0.45) | — | |
| SCHEMBL10926488 | 0.64 | MEN1 (0.39) | — | |
| SCHEMBL9674007 | 0.61 | MEN1 (0.37) | — | |
| SCHEMBL10904924 | 0.61 | CDC25B (0.47) | — | |
| SCHEMBL3678137 | 0.61 | ESR1 (0.42) | — | |
| SCHEMBL236503 | 0.59 | CDC25B (0.46) | — | |
| SCHEMBL2627989 | 0.59 | MEN1 (0.73) | — | |
| SCHEMBL29409540 | 0.59 | MEN1 (0.73) | — | |
| SCHEMBL1310003 | 0.59 | CDC25B (0.46) | — | |
| SCHEMBL30051046 | 0.59 | CDC25B (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793989-A1 | THIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2021-03-24 | — | — | EP | disclosed |
| EP-0853083-B1 | Pyridylfuran and pyridylthiophene compounds and pharmaceutical use thereof | PFIZER (US) | 2001-09-12 | — | — | EP | disclosed |
| US-4127665-A | ALDOSE REDUCTASE INHIBITORS, TREATMENT OF CHROMIC DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1978-11-28 | — | — | US | disclosed |