Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 6/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150759 | 0.88 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL4741409 | 0.85 | TSHR (0.75) | TSHRPTPN1CDC25BALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7846976 | 0.83 | TSHR (0.56) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL7848859 | 0.82 | TSHR (0.59) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL7848703 | 0.81 | TSHR (0.63) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL22531831 | 0.81 | TSHR (0.63) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL2569253 | 0.81 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL29671336 | 0.81 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL4465565 | 0.80 | CDC25B (0.69) | TSHRCDC25BALDH1A1HSD17B10CLEC4M | |
| SCHEMBL9547639 | 0.80 | PTPN1 (0.62) | TSHRPTPN1HPGDSALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140946-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035919-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-06-22 | — | — | WO | disclosed |