Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.36 |
| ▸ | ITGAL | P20701 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199489 | 0.92 | ITGB2 (0.48) | ALDH1A1LMNARAB9AMAPTITGB2 | |
| SCHEMBL6197412 | 0.86 | ITGB2 (0.50) | ALDH1A1LMNARAB9AMAPTITGB2 | |
| SCHEMBL7617894 | 0.82 | ITGB2 (0.42) | ALDH1A1LMNARAB9AMAPTGPR119 | |
| SCHEMBL27475640 | 0.81 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL6201823 | 0.79 | ITGB2 (0.49) | ALDH1A1LMNARAB9AITGB2ICAM1 | |
| SCHEMBL5830356 | 0.78 | ITGB2 (0.50) | ALDH1A1LMNARAB9AMAPTGPR119 | |
| SCHEMBL27514900 | 0.78 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL6198855 | 0.78 | ITGB2 (0.48) | ALDH1A1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6196430 | 0.78 | ITGB2 (0.49) | ALDH1A1LMNARAB9AITGB2ICAM1 | |
| SCHEMBL6197324 | 0.77 | ITGB2 (0.52) | ALDH1A1LMNARAB9AITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | claimed |