Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9144124 | 0.85 | DPP4 (0.47) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL9144116 | 0.85 | DPP4 (0.47) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL8182327 | 0.82 | KMT2A (0.51) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL7849661 | 0.82 | KMT2A (0.51) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL7848976 | 0.79 | KCNH2 (0.46) | KMT2ALMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9686011 | 0.78 | KMT2A (0.67) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL9044442 | 0.78 | KMT2A (0.67) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL9685896 | 0.78 | KMT2A (0.67) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL9685533 | 0.78 | DPP4 (0.54) | DPP4KMT2AEPHA2FLT4GSK3B | |
| SCHEMBL9685951 | 0.78 | DPP4 (0.54) | DPP4KMT2AEPHA2FLT4GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911336-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-6017911-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0911336-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-04-28 | — | — | EP | disclosed |