Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229878 | 0.76 | POLB (1.00) | POLBALDH1A1CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL14667537 | 0.76 | POLB (0.57) | POLBALDH1A1CYP1A2SMN1; SMN2CYP2D6 | |
| SCHEMBL637051 | 0.76 | POLB (0.57) | POLBALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL637050 | 0.76 | POLB (0.57) | POLBALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL18419421 | 0.76 | POLB (1.00) | POLBALDH1A1CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL11503506 | 0.76 | POLB (0.57) | POLBALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL18920836 | 0.72 | ATM (0.61) | POLBALDH1A1SMN1; SMN2IDO1CES2 | |
| SCHEMBL18920837 | 0.72 | ATM (0.61) | POLBALDH1A1SMN1; SMN2IDO1CES2 | |
| SCHEMBL18933388 | 0.72 | ATM (0.61) | POLBALDH1A1SMN1; SMN2IDO1CES2 | |
| SCHEMBL3455076 | 0.72 | POLB (0.52) | POLBALDH1A1SMN1; SMN2IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048228-A | Substituted cyanamidic compounds | UOP INC. (US) | 1977-09-13 | — | — | US | claimed |
| EP-1163239-A1 | MODIFIED AMINO-ACID AMIDES AS CGRP ANTAGONISTS | Boehringer Ingelheim Pharma KG (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055154-A1 | MODIFIED AMINO-ACID AMIDES AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-21 | — | — | WO | disclosed |
| US-4048228-A | Substituted cyanamidic compounds | UOP INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048228-A | Substituted cyanamidic compounds | UOP INC. (US) | 1977-09-13 | — | — | US | disclosed |