Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222147 | 0.86 | KDM4E (0.54) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL13042362 | 0.83 | HDAC3 (0.57) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9039448 | 0.81 | TSHR (0.61) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL6343179 | 0.80 | KDM4E (0.56) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9039712 | 0.80 | HDAC3 (0.48) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL4658952 | 0.80 | KDM4E (0.59) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL17273989 | 0.78 | HDAC3 (0.52) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL2781925 | 0.78 | KDM4E (0.61) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL4591341 | 0.78 | HDAC3 (0.58) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL4591337 | 0.78 | HDAC3 (0.58) | HDAC3HDAC1HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274692-C | Total synthesizing meethod for pyrrole heterocyclic alkaloid aldisin | UNIV JINAN (CN) | 2006-09-13 | — | — | CN | disclosed |
| EP-0711773-B1 | HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE | SUNTORY LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5621099-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0711773-A1 | HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE | SUNTORY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |