Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849654 | 1.00 | PDE4B (0.56) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL7849655 | 1.00 | PDE4B (0.56) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL14801527 | 0.92 | USP30 (0.48) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL14801528 | 0.92 | USP30 (0.48) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL14801708 | 0.92 | USP30 (0.48) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL12426644 | 0.90 | PDE4B (0.57) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL2182997 | 0.90 | PDE4B (0.57) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL16727951 | 0.88 | PDE4B (0.57) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL14704987 | 0.88 | PDE4B (0.57) | PDE4BPDK1PDK2PDK3PDK4 | |
| SCHEMBL13568021 | 0.88 | PDE4B (0.57) | PDE4BPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726269-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES AND SALTS THEREOF | KAKEN PHARMA CO LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5668147-A | ANTIBIOTICS, BACTERICIDES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0726269-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |