Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.77 |
| ▸ | PPARA | Q07869 | 15/20 | 0.77 |
| ▸ | PPARD | Q03181 | 6/20 | 0.62 |
| ▸ | TSPO | P30536 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527301 | 1.00 | PPARG (0.77) | PPARGPPARAPPARDTSPOCNR2 | |
| SCHEMBL7527676 | 0.95 | PPARA (0.74) | PPARGPPARAPPARDTSPO | |
| SCHEMBL7532542 | 0.91 | PPARA (0.72) | PPARGPPARAPPARD | |
| SCHEMBL7852911 | 0.91 | PPARA (0.72) | PPARGPPARAPPARD | |
| SCHEMBL7535734 | 0.89 | PPARG (0.62) | PPARGPPARAPPARDTSPO | |
| SCHEMBL7856304 | 0.87 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7528811 | 0.87 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7535616 | 0.86 | PPARA (0.66) | PPARGPPARAPPARD | |
| SCHEMBL7855869 | 0.85 | PPARA (0.83) | PPARGPPARAPPARD | |
| SCHEMBL7527255 | 0.85 | PPARA (0.83) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123279-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-08-16 | — | — | EP | claimed |
| WO-2000023425-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-04-27 | — | — | WO | claimed |