Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 13/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230466 | 0.83 | SNCA (0.47) | SNCAMAPTCDK4CCND1ACHE | |
| SCHEMBL7231199 | 0.83 | SNCA (0.49) | SNCAMAPTCDK4CCND1ACHE | |
| SCHEMBL7222957 | 0.83 | SNCA (0.46) | SNCAMAPT | |
| SCHEMBL7852192 | 0.83 | F10 (0.56) | SNCAF10CDK4CCND1KDM4E | |
| SCHEMBL7229732 | 0.83 | SNCA (0.47) | SNCAMAPTCDK4CCND1ACHE | |
| SCHEMBL7224298 | 0.83 | CDK4 (0.54) | SNCAF10MAPTCDK4CCND1 | |
| SCHEMBL7223332 | 0.82 | SNCA (0.49) | SNCAMAPT | |
| SCHEMBL7225068 | 0.82 | SNCA (0.49) | SNCAMAPTCDK4CCND1ACHE | |
| SCHEMBL7222941 | 0.81 | SNCA (0.47) | SNCAF10MAPTCDK4CCND1 | |
| SCHEMBL7230428 | 0.81 | SNCA (0.46) | SNCAMAPTCDK4CCND1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140901-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039087-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-06 | — | — | WO | disclosed |