SCHEMBL7854023

SCHEMBL7854023

C1CCC([C]2NCCN2)C1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.41
HRH4 Q9H3N8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7855758 0.97 NISCH (0.44) NISCHKDM4EALDH1A1HPGDHSD17B10
SCHEMBL7852100 0.97 NISCH (0.44) NISCHKDM4EALDH1A1HPGDHSD17B10
SCHEMBL7855667 0.97 NISCH (0.44) NISCHKDM4EALDH1A1HPGDHSD17B10
SCHEMBL7854306 0.94
SCHEMBL7856417 0.87
SCHEMBL6319373 0.61
SCHEMBL27829921 0.61 NISCH (0.35) NISCHHRH4
SCHEMBL27856872 0.60 NISCH (0.34) NISCH
SCHEMBL21391659 0.60 NISCH (0.95) NISCHALDH1A1
SCHEMBL310610 0.60 NISCH (0.39) NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719258-B1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMA CO LTD (JP) 2001-10-31 EP disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0719258-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-07-03 EP disclosed
WO-1996002508-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-02-01 WO disclosed