Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 13/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892056 | 0.90 | SNCA (0.68) | SNCAIDO1ABCG2MTNR1AMTNR1B | |
| SCHEMBL7845319 | 0.89 | SNCA (0.58) | SNCAMTNR1AMTNR1BTSHR | |
| SCHEMBL7852712 | 0.89 | SNCA (0.56) | SNCAMTNR1AMTNR1BLMNATSHR | |
| SCHEMBL7845344 | 0.82 | SNCA (0.49) | SNCAMTNR1AMTNR1B | |
| SCHEMBL892663 | 0.81 | SNCA (0.58) | SNCAABCG2MTNR1AMTNR1BMEN1 | |
| SCHEMBL891988 | 0.79 | SNCA (0.68) | SNCAMTNR1AMTNR1B | |
| SCHEMBL892778 | 0.79 | SNCA (0.66) | SNCAMTNR1AMTNR1B | |
| SCHEMBL892789 | 0.79 | SNCA (0.59) | SNCAABCG2 | |
| SCHEMBL892644 | 0.78 | SNCA (0.70) | SNCAIDO1ABCG2MTNR1AMTNR1B | |
| SCHEMBL892046 | 0.77 | SNCA (0.67) | SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142801-A1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2010-12-16 | — | — | WO | disclosed |