Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.51 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395998 | 0.82 | GSK3B (0.59) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4400512 | 0.81 | GSK3B (0.53) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4400510 | 0.76 | GSK3B (0.39) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4400377 | 0.73 | GSK3B (0.62) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4393974 | 0.72 | GSK3B (0.75) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4393977 | 0.70 | GSK3B (0.69) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL13300067 | 0.70 | GSK3B (0.59) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4404427 | 0.70 | GSK3B (0.64) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4396003 | 0.69 | GSK3B (0.61) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL6069383 | 0.69 | GSK3B (0.54) | GSK3BCCNB2CDK1CCNB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087963-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | Chiron Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |