Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851818 | 0.86 | CDK4 (0.42) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7224485 | 0.81 | SNCA (0.44) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7229744 | 0.80 | SNCA (0.49) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7225068 | 0.79 | SNCA (0.49) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7229562 | 0.79 | SNCA (0.46) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7223379 | 0.78 | SNCA (0.44) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7231199 | 0.78 | SNCA (0.49) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7224390 | 0.78 | CDK4 (0.53) | SNCACDK4CCND1TRPV1POLB | |
| SCHEMBL7231644 | 0.77 | SNCA (0.42) | SNCAMAPTCDK4CCND1TRPV1 | |
| SCHEMBL7222956 | 0.77 | MAPT (0.55) | SNCAMAPTCDK4CCND1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140901-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039087-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-06 | — | — | WO | disclosed |