Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.86 |
| ▸ | PPARA | Q07869 | 17/20 | 0.86 |
| ▸ | PPARD | Q03181 | 5/20 | 0.86 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530870 | 1.00 | PPARG (0.86) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7533813 | 0.95 | PPARG (0.77) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL30583368 | 0.92 | PPARA (1.00) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL4316922 | 0.92 | PPARA (1.00) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL4316930 | 0.92 | PPARA (1.00) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7527487 | 0.92 | PPARG (0.88) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7536112 | 0.92 | PPARG (0.72) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7529590 | 0.90 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL7852634 | 0.88 | PPARG (0.80) | PPARGPPARAPPARD | |
| SCHEMBL7532140 | 0.88 | PPARG (0.80) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123279-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-08-16 | — | — | EP | claimed |
| WO-2000023425-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-04-27 | — | — | WO | claimed |