Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 19/20 | 0.82 |
| ▸ | SELE | P16581 | 19/20 | 0.82 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052496 | 0.90 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7052501 | 0.90 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7060330 | 0.82 | ICAM1 (0.84) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7060335 | 0.82 | ICAM1 (0.84) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7054708 | 0.76 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7052402 | 0.67 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7057146 | 0.66 | ICAM1 (0.80) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7057661 | 0.65 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL5550624 | 0.65 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL7056197 | 0.63 | ICAM1 (1.00) | ICAM1SELEVCAM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |