Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867305 | 0.81 | HPGD (0.60) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL14740086 | 0.79 | HSD17B10 (0.54) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL8871621 | 0.79 | MEN1 (0.54) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL5089332 | 0.79 | MEN1 (0.54) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL11414055 | 0.77 | MEN1 (0.51) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL12419714 | 0.77 | HPGD (0.64) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL16740930 | 0.76 | MEN1 (0.54) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL1027011 | 0.76 | HPGD (0.68) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL2146965 | 0.76 | MEN1 (0.68) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| Bromide SCHEMBL29283499 | 0.76 | MEN1 (0.50) | MEN1HPGDKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087963-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | Chiron Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |