SCHEMBL7855432

SCHEMBL7855432

CCCc1n[nH]c(C(=O)O)c1C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.42
HCAR3 P49019 3/20 0.37
ALDH1A1 P00352 2/20 0.34
ALPL P05186 1/20 0.34
HTT P42858 1/20 0.33
GLA P06280 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23384516 0.85 HCAR2 (0.35) HCAR2ALDH1A1ALPLHTTGLA
SCHEMBL2589542 0.85 HCAR2 (0.47) HCAR2HCAR3ALDH1A1ALPLRAB9A
SCHEMBL27614783 0.84 SMN1; SMN2 (0.35) HCAR2ALDH1A1ALPLHTTGLA
SCHEMBL6110016 0.84 HCAR2 (0.36) HCAR2ALDH1A1RAB9ADAO
SCHEMBL17294915 0.81 HCAR2 (0.42) HCAR2HCAR3ALDH1A1ALPLHTT
SCHEMBL27816079 0.81 HCAR2 (0.44) HCAR2HCAR3ALDH1A1HTTMAPT
SCHEMBL6109836 0.81 HCAR2 (0.34) HCAR2HCAR3ALDH1A1RAB9ADAO
SCHEMBL3949940 0.80 HCAR2 (0.45) HCAR2HCAR3ALDH1A1ALPLHTT
SCHEMBL6109927 0.80 HCAR2 (0.33) HCAR2HCAR3ALDH1A1RAB9A
SCHEMBL6111302 0.80 HCAR2 (0.33) HCAR2ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1606557-A Deuterated pyrazolopyrimidinones and drugs containing said compounds TURICUM DRUG DEV AG (CH) 2005-04-13 CN disclosed
WO-2001022918-A2 METHOD OF PREPARATION OF SILDENAFIL INST FARMACEUTYCZNY (PL) 2001-04-05 WO disclosed