Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996407 | 0.84 | CHEK1 (0.59) | CHEK1 | |
| SCHEMBL6992572 | 0.82 | CHEK1 (0.60) | CHEK1 | |
| SCHEMBL7000769 | 0.76 | CHEK1 (0.64) | CHEK1 | |
| Hydrochloric Acid SCHEMBL7089690 | 0.75 | CHEK1 (0.62) | CHEK1 | |
| SCHEMBL7092402 | 0.73 | KMT2A (0.55) | CHEK1 | |
| SCHEMBL6992949 | 0.73 | KDR (0.54) | CHEK1 | |
| SCHEMBL7092465 | 0.73 | KDR (0.56) | CHEK1 | |
| SCHEMBL4816267 | 0.72 | CHEK1 (0.71) | CHEK1 | |
| SCHEMBL7698778 | 0.72 | KDR (0.52) | CHEK1 | |
| SCHEMBL7092071 | 0.72 | PARP1 (0.62) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127051-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | claimed |
| WO-2000027822-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | claimed |