⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753505 | 0.75 | — | — | |
| SCHEMBL1562737 | 0.71 | — | — | |
| SCHEMBL6408489 | 0.71 | — | — | |
| SCHEMBL1562714 | 0.71 | — | — | |
| SCHEMBL6408493 | 0.71 | — | — | |
| SCHEMBL1562715 | 0.71 | — | — | |
| SCHEMBL3106925 | 0.65 | — | — | |
| SCHEMBL67264 | 0.64 | — | — | |
| SCHEMBL696634 | 0.63 | — | — | |
| SCHEMBL8336020 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112266-A1 | SUBSTITUTED 4-AMINO-2-ARYL-PYRIMIDINES, THEIR PRODUCTION AND USE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | Aventis Pharma Deutschland GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000009496-A1 | SUBSTITUTED 4-AMINO-2-ARYL-PYRIMIDINES, THEIR PRODUCTION AND USE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-02-24 | — | — | WO | disclosed |