SCHEMBL7856969

SCHEMBL7856969

C=CCOC(=O)C[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 2/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 8/20 0.36
HSD17B10 Q99714 5/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 4/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
SNCA P37840 1/20 0.34
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16430762 0.81 TSHR (0.55) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL1155518 0.79 TSHR (0.37) TSHRTDP1CYP3A4MAPTCACNA1B
SCHEMBL7953908 0.79 MEN1 (0.31) TSHRPKMMAPTHSD17B10
SCHEMBL10011525 0.78 TDP1 (0.51) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL28456824 0.77 TSHR (0.50) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL10549299 0.77 TDP1 (0.42) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL194711 0.76
SCHEMBL57069 0.75 TSHR (0.52) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL56403 0.75 TSHR (0.63) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL4793964 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114622316-B Polylactic acid bio-based functional coated yarn for sweater and preparation method thereof 安徽德和织造有限公司 2023-09-01 CN claimed
EP-0790998-A1 AZO DERIVATIVES OF 5-AMINOSALICYLIC ACID FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE J. URIACH & CIA. S.A. (ES) 1997-08-27 EP claimed
WO-1997009329-A1 AZO DERIVATIVES OF 5-AMINOSALICYLIC ACID FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE J. URIACH & CIA. S.A. (ES) 1997-03-13 WO claimed
CN-114622316-B Polylactic acid bio-based functional coated yarn for sweater and preparation method thereof 安徽德和织造有限公司 2023-09-01 CN disclosed
WO-2021129583-A1 POLYMER ELECTROLYTE, AND LITHIUM ION BATTERY COMPRISING SAME 珠海冠宇电池股份有限公司 2021-07-01 WO disclosed
EP-0790998-B1 AZO DERIVATIVES OF 5-AMINOSALICYLIC ACID FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE URIACH & CIA SA J (ES) 2001-01-17 EP disclosed
US-5747477-A INFLAMMATORY BOWEL DISEASE, GASTROINTESTINAL DISORDERS, CROHN*S DISEASE J. URIACH & CIA S.A. (ES) 1998-05-05 US disclosed
EP-0790998-A1 AZO DERIVATIVES OF 5-AMINOSALICYLIC ACID FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE J. URIACH & CIA. S.A. (ES) 1997-08-27 EP disclosed
WO-1997009329-A1 AZO DERIVATIVES OF 5-AMINOSALICYLIC ACID FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE J. URIACH & CIA. S.A. (ES) 1997-03-13 WO disclosed
US-5061762-A MODIFIED POLY(ORGANO-ORGANOSILOXANES) WITH COMB OR BLOCK STRUCTURES AND A PROCESS FOR THEIR PREPARATION WACKER-CHEMIE GMBH (DE) 1991-10-29 US disclosed
US-4874782-A PHOSPHOLIPASE INHIBITORS ELI LILLY AND COMPANY (US) 1989-10-17 US disclosed
EP-0209274-A2 Furanone derivatives ELI LILLY AND COMPANY (US) 1987-01-21 EP disclosed