Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KLK7 | P49862 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962640 | 0.91 | MEN1 (0.84) | MEN1KMT2APOLBKLK7TP53 | |
| SCHEMBL1962638 | 0.91 | MEN1 (0.84) | MEN1KMT2APOLBKLK7TP53 | |
| SCHEMBL6603407 | 0.84 | KMT2A (0.77) | MEN1KMT2APOLBLMNATP53 | |
| SCHEMBL6603409 | 0.84 | KMT2A (0.77) | MEN1KMT2APOLBLMNATP53 | |
| SCHEMBL6605741 | 0.79 | MEN1 (0.75) | MEN1KMT2APOLBLMNATP53 | |
| SCHEMBL6605747 | 0.79 | MEN1 (0.75) | MEN1KMT2APOLBLMNATP53 | |
| Piriqualone SCHEMBL2109756 | 0.79 | MEN1 (1.00) | MEN1KMT2APOLBLMNATP53 | |
| SCHEMBL6600719 | 0.78 | MEN1 (0.61) | MEN1KMT2A | |
| SCHEMBL6600721 | 0.78 | MEN1 (0.61) | MEN1KMT2A | |
| SCHEMBL6601529 | 0.76 | MEN1 (0.58) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303615-B1 | FOR THERAPY AND PROPHYLAXIS OF NEURODEGENERATIVE DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS, CONVULSIONS | PFIZER INC | 2001-10-16 | — | — | US | disclosed |