Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10538981 | 0.98 | TP53 (0.33) | TP53FFAR3LCKFYN | |
| Acetic Acid SCHEMBL10787618 | 0.98 | TP53 (0.33) | TP53FFAR3LCKFYN | |
| Acetic Acid SCHEMBL9490074 | 0.93 | TP53 (0.33) | TP53FFAR3LCKFYN | |
| Acetic Acid SCHEMBL7849426 | 0.93 | TP53 (0.33) | TP53FFAR3LCKFYN | |
| SCHEMBL8760845 | 0.91 | — | — | |
| SCHEMBL8985737 | 0.91 | — | — | |
| Acetic Acid SCHEMBL1766203 | 0.70 | CA1 (0.43) | — | |
| Acetic Acid SCHEMBL9489112 | 0.70 | CA1 (0.38) | — | |
| SCHEMBL11376836 | 0.69 | — | — | |
| SCHEMBL14541621 | 0.68 | TP53 (0.32) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721148-B1 | Automatic processing machine for light-sensitive silver halide photographic materials | KONISHIROKU PHOTO IND (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0537365-B1 | AUTOMATIC DEVELOPING APPARATUS FOR SILVER HALIDE PHOTOSENSITIVE | KONISHIROKU PHOTO IND (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0721148-A2 | Automatic processing machine for light-sensitive silver halide photographic materials | KONICA CORPORATION (JP) | 1996-07-10 | — | — | EP | disclosed |
| EP-0537365-A1 | AUTOMATIC DEVELOPING APPARATUS FOR SILVER HALIDE PHOTOSENSITIVE | KONICA CORPORATION (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-4707434-A | Color image forming method comprising processing with a bleach-fixing solution | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-11-17 | — | — | US | disclosed |