SCHEMBL7859

SCHEMBL7859

NC(=O)CCCc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.72
HDAC3 O15379 3/20 0.72
HDAC2 Q92769 3/20 0.72
HDAC8 Q9BY41 3/20 0.72
HDAC6 Q9UBN7 3/20 0.72
HDAC5 Q9UQL6 3/20 0.72
HDAC4 P56524 2/20 0.72
HDAC7 Q8WUI4 2/20 0.72
HDAC10 Q969S8 2/20 0.72
HDAC11 Q96DB2 2/20 0.72
HDAC9 Q9UKV0 2/20 0.72
MAPK1 P28482 1/20 0.72
ADRA1A P35348 1/20 0.72
SLC6A3 Q01959 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
TDP1 Q9NUW8 2/20 0.64
NPC1 O15118 1/20 0.64
CASP3 P42574 1/20 0.64
RAB9A P51151 1/20 0.64
SENP8 Q96LD8 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30882401 0.98 HDAC1 (0.69) HDAC1HDAC3HDAC2HDAC8HDAC6
Water SCHEMBL28210512 0.98 HDAC1 (0.69) HDAC1HDAC3HDAC2HDAC8HDAC6
Hydrochloric Acid SCHEMBL23062929 0.98 HDAC1 (0.69) HDAC1HDAC3HDAC2HDAC8HDAC6
Hydrochloric Acid SCHEMBL30882658 0.98 HDAC1 (0.69) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL5020709 0.96 HDAC1 (0.67) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL1285919 0.93 MAPT (0.70) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL1327206 0.91 MAPT (0.74) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL5981360 0.91 MAPT (0.74) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL1285525 0.91 MAPT (0.74) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL21359026 0.91 MAPT (0.74) HDAC1HDAC3HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3224 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 US claimed
US-12208071-B2 Glucagon receptor antagonists LIGAND PHARMACEUTICALS INCORPORATED (US) 2025-01-28 US claimed
US-12186329-B2 Compositions and methods related to cholic acid 7-sulfate as a treatment for diabetes PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-01-07 US claimed
US-12180188-B2 Antifibrotic compounds and related methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2024-12-31 US claimed
US-20240316048-A1 Prevention of Pancreatic Cell Degeneration MELIOR PHARMACEUTICALS I, INC. 2024-09-26 US claimed
US-12070461-B2 Methods and formulations for modulating Lyn kinase activity and treating related disorders MELIOR PHARMACEUTICALS I, INC. (US) 2024-08-27 US claimed
US-20230263821-A1 Treatment Of Increased Lipid Levels With Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) Inhibitors UNIVERSITY OF MARYLAND, BALTIMORE 2023-08-24 US claimed
EP-4153177-A1 ANTIFIBROTIC COMPOUNDS AND RELATED METHODS Florida State University Research Foundation, Inc. (US) 2023-03-29 EP claimed
US-20230090542-A1 Antifibrotic Compounds And Related Methods THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES 2023-03-23 US claimed
US-11548874-B2 Antifibrotic compounds and related methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-01-10 US claimed
WO-1999033855-A1 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES, METHOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-08 WO claimed
US-5859037-A MIXTURE SYNERGISTIC FOR THE TREATMENT OF NON-INSULIN DEPENDENT DIABETES MELLITUS IN HUMANS, WHICH ALSO IMPROVES GLYCEMIC CONTROL WARNER-LAMBERT COMPANY (US) 1999-01-12 US claimed
EP-0610744-B1 Sulfonamide aminomethylene derivatives as immunosuppressants BAYER AG (US) 1998-11-04 EP claimed
WO-1998036755-A1 SULFONYLUREA-GLITAZONE SYNERGISTIC COMBINATIONS FOR DIABETES WARNER LAMBERT COMPANY (US) 1998-08-27 WO claimed
US-5686469-A ANTIINFLAMMATORY AGENTS MILES INC. (US) 1997-11-11 US claimed
CN-1112117-A Imidazole-containing inhibitors of farnesyl protein transferase BRISTOL MYERS SQUIBB CO (US) 1995-11-22 CN claimed
EP-0298758-B1 Hydroquinonylphenyl butyric acid amide derivative SUNTORY LTD (JP) 1995-06-28 EP claimed
EP-0610745-A2 Novel aminomethylene derivatives as immunosuppressants Bayer Corporation (US) 1994-08-17 EP claimed
EP-0316820-B1 THIAZOLE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-22 EP claimed
US-4921887-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-01 US claimed