Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.56 |
| ▸ | CDK2 | P24941 | 6/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.56 |
| ▸ | CCNT2 | O60583 | 3/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.56 |
| ▸ | CDK9 | P50750 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3444997 | 0.72 | CCNE1 (0.75) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15117729 | 0.72 | CCNE1 (1.00) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL2911156 | 0.70 | CCNE1 (0.56) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15941138 | 0.69 | CCNE1 (0.60) | CCNE1CDK2CCNT1CCNE2CDK9 | |
| SCHEMBL2911161 | 0.69 | CDK2 (0.66) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL3445797 | 0.69 | CCNE1 (0.70) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15118198 | 0.69 | CCNE1 (0.81) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15117849 | 0.68 | CCNE1 (0.85) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15117834 | 0.68 | CCNE1 (0.78) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL3445169 | 0.68 | CDK2 (0.69) | CCNE1CDK2CCNT1CCNT2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070512-A1 | Substituted 6-(2-hydroxybenzylamino)purine Derivatives, Their Use as Medicaments and Compositions Containing These Derivatives | BIOPATTERNS, S.R.O (CZ) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070512-A1 | Substituted 6-(2-hydroxybenzylamino)purine Derivatives, Their Use as Medicaments and Compositions Containing These Derivatives | CDK6, CCNI, CDK2 | CCNE1 80/4885CDK2 3/4885CCNT1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.