Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 11/20 | 0.50 |
| ▸ | VHL | P40337 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074846 | 0.96 | CTSC (0.48) | CTSCVHLOPRM1OPRD1OPRK1 | |
| SCHEMBL2074847 | 0.96 | CTSC (0.48) | CTSCVHLOPRM1OPRD1OPRK1 | |
| SCHEMBL3772312 | 0.91 | CTSC (0.53) | CTSCVHLOPRM1OPRD1OPRK1 | |
| SCHEMBL2073323 | 0.89 | CTSC (0.46) | CTSCVHLOPRM1OPRD1OPRK1 | |
| SCHEMBL2073322 | 0.89 | CTSC (0.46) | CTSCVHLOPRM1OPRD1OPRK1 | |
| SCHEMBL7858106 | 0.89 | CTSC (0.64) | CTSCKCNH2 | |
| SCHEMBL2074016 | 0.87 | CTSC (0.51) | CTSCVHLOPRM1OPRD1OPRK1 | |
| SCHEMBL2075395 | 0.85 | CTSC (0.63) | CTSCKCNH2 | |
| SCHEMBL2075394 | 0.85 | CTSC (0.63) | CTSCKCNH2 | |
| SCHEMBL12422472 | 0.81 | CTSC (0.47) | CTSCKCNH2MC4RMC5RJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142985-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL]PIPERIDIN-2-YLCARBOXMIDE COMPOUNDS 761 | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | WO | disclosed |