Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756772 | 0.92 | PIK3CA (0.57) | PIK3CAPRKDCCREBBP | |
| SCHEMBL3762451 | 0.84 | PIK3CA (0.60) | PIK3CAPRKDCCREBBP | |
| SCHEMBL3754736 | 0.81 | PIK3CA (0.61) | PIK3CAPRKDC | |
| SCHEMBL3748041 | 0.79 | PIK3CA (0.62) | PIK3CAPRKDCCREBBP | |
| SCHEMBL3755298 | 0.79 | PIK3CA (0.76) | PIK3CA | |
| SCHEMBL3757004 | 0.78 | PIK3CA (0.65) | PIK3CAPRKDCCREBBP | |
| Hydrochloric Acid SCHEMBL3762167 | 0.77 | PIK3CA (0.64) | PIK3CAPRKDCCREBBP | |
| SCHEMBL3753793 | 0.77 | PIK3CA (0.76) | PIK3CA | |
| SCHEMBL3755378 | 0.77 | PIK3CA (0.77) | PIK3CAPRKDCCREBBP | |
| SCHEMBL3755685 | 0.77 | PIK3CA (0.64) | PIK3CAPRKDCCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |