Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22390581 | 0.87 | MAPT (0.37) | TDP1TSHRTP53LMNAALDH1A1 | |
| SCHEMBL27341 | 0.87 | MAPT (0.37) | TDP1TSHRTP53LMNAALDH1A1 | |
| SCHEMBL5585363 | 0.87 | MAPT (0.37) | TDP1TSHRTP53LMNAALDH1A1 | |
| Bromide SCHEMBL7615302 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 | |
| Iodide SCHEMBL8077383 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839089 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 | |
| SCHEMBL9796698 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 | |
| Bromide SCHEMBL8064378 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 | |
| SCHEMBL16207394 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10904239 | 0.85 | MAPT (0.36) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764739-B1 | Moisture-proof paper sheet | OJI PAPER CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5695608-A | COATING FORMED FROM SYNTHETIC RESIN CONTAINING CRYSTALLINE PHYLLOSILICATE COMPOUND PARTICLES AND MOISTURE PROOFNESS ENHANCING AGENT | NEW OJI PAPER CO., INC. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0764739-A2 | Moisture-proof paper sheet | NEW OJI PAPER CO., LTD. (JP) | 1997-03-26 | — | — | EP | disclosed |
| EP-0419945-B1 | Aqueous polyurethane dispersions and adhesives based thereon | MILES INC (US) | 1994-08-24 | — | — | EP | disclosed |
| US-5124400-A | A polyurethane-urea using a diamine chain extender; increased softening point; durability | MILES INC. (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0419945-A2 | Aqueous polyurethane dispersions and adhesives based thereon | MILES INC. (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4608413-A | BLEND OF POLYETHERURETHANE AND POLYESTERURETHANE COPOLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-08-26 | — | — | US | disclosed |