⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787114 | 0.83 | — | — | |
| SCHEMBL8032075 | 0.83 | — | — | |
| SCHEMBL18316486 | 0.75 | — | — | |
| SCHEMBL27535097 | 0.74 | — | — | |
| SCHEMBL6369542 | 0.71 | TP53 (0.30) | — | |
| SCHEMBL10456852 | 0.70 | — | — | |
| SCHEMBL1208278 | 0.69 | — | — | |
| SCHEMBL19433847 | 0.67 | — | — | |
| SCHEMBL3908898 | 0.67 | — | — | |
| SCHEMBL28026159 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066245-A4 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | ADVANCED MEDICINE INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1066245-A1 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | Advanced Medicine, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051565-A9 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | ADVANCED MEDICINE INC (US) | 1999-12-02 | — | — | WO | disclosed |
| WO-1999051565-A1 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | ADVANCED MEDICINE, INC. (US) | 1999-10-14 | — | — | WO | disclosed |