Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7862248 | 0.99 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1817928 | 0.90 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL4282932 | 0.89 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7382150 | 0.87 | PDE4B (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL196243 | 0.87 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29623586 | 0.87 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7858949 | 0.87 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7853215 | 0.87 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL154624 | 0.86 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL30543740 | 0.86 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045849-A4 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO CELTIQUE SA (LU) | 2001-10-31 | — | — | EP | claimed |
| EP-1045849-A1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | Euro-Celtique S.A. (LU) | 2000-10-25 | — | — | EP | claimed |
| WO-1999031102-A1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO-CELTIQUE, S.A. (LU) | 1999-06-24 | — | — | WO | claimed |
| EP-1045849-A4 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO CELTIQUE SA (LU) | 2001-10-31 | — | — | EP | disclosed |
| EP-1045849-A1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | Euro-Celtique S.A. (LU) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999031102-A1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO-CELTIQUE, S.A. (LU) | 1999-06-24 | — | — | WO | disclosed |