Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 12/20 | 0.60 |
| ▸ | DRD2 | P14416 | 10/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861298 | 1.00 | FYN (0.61) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL8693679 | 0.86 | DRD3 (0.63) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL7862496 | 0.84 | DRD3 (0.60) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL8899133 | 0.84 | DRD3 (0.60) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL7862705 | 0.84 | DRD3 (0.60) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL7862463 | 0.84 | DRD3 (0.60) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL7449385 | 0.81 | DRD3 (0.78) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| SCHEMBL9522498 | 0.80 | DRD3 (0.57) | FYNDRD3DRD2 | |
| SCHEMBL7402515 | 0.80 | FYN (0.69) | FYNDRD3DRD2CYP2D6ALDH1A1 | |
| Bromide SCHEMBL8688813 | 0.79 | DRD3 (0.78) | FYNDRD3DRD2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |