Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607971 | 1.00 | HCRTR1 (0.44) | HCRTR1HCRTR2OPRK1PIK3CDPIK3CB | |
| SCHEMBL610084 | 0.85 | HCRTR2 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL607935 | 0.82 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL608855 | 0.82 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL610630 | 0.82 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL7866579 | 0.81 | HCRTR2 (0.41) | HCRTR1HCRTR2OPRK1 | |
| SCHEMBL607593 | 0.81 | HCRTR2 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL608175 | 0.81 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL7869493 | 0.81 | HCRTR2 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL609561 | 0.81 | HCRTR2 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122151-A1 | 3 -AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-10-28 | — | — | WO | disclosed |