SCHEMBL7861981

COC(=O)C[C@@H]1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C[C@H](CC(=O)OC)N1.COC(=O)C[C@H]1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C[C@H](CC(=O)OC)N1

nearest known ligand 0.43

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	GLRA3	O75311	3/20	0.43

▸	GLRB	P48167	3/20	0.43

▸	F10	P00742	10/20	0.41

▸	ATM	Q13315	1/20	0.41

▸	LMNA	P02545	2/20	0.40

▸	F2	P00734	2/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	GAA	P10253	1/20	0.40

▸	PKM	P14618	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	TP53	P04637	1/20	0.40

▸	MAPT	P10636	1/20	0.40

▸	MEN1	O00255	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	POLB	P06746	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6730470	1.00	GLRA3 (0.43)	GLRA3GLRBF10ATMLMNA
SCHEMBL6730844	1.00	GLRA3 (0.43)	GLRA3GLRBF10ATMLMNA
SCHEMBL6730466	1.00	GLRA3 (0.43)	GLRA3GLRBF10ATMLMNA
SCHEMBL6730840	1.00	GLRA3 (0.43)	GLRA3GLRBF10ATMLMNA
SCHEMBL6198614	0.88	F10 (0.44)	F10ATMLMNAF2TP53
SCHEMBL6725657	0.81	F10 (0.54)	F10
SCHEMBL6730790	0.81	F10 (0.54)	F10
SCHEMBL6725662	0.81	F10 (0.54)	F10
SCHEMBL5729062	0.79	F10 (0.41)	F10F2
SCHEMBL6726016	0.78	F10 (0.44)	F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1104754-A1	NOVEL SULFONYL DERIVATIVES	DAIICHI PHARMACEUTICAL CO., LTD. (JP)	2001-06-06	—	—	EP	disclosed