Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.60 |
| ▸ | TUBB | P07437 | 3/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.60 |
| ▸ | MC1R | Q01726 | 7/20 | 0.54 |
| ▸ | MC5R | P33032 | 3/20 | 0.54 |
| ▸ | MC3R | P41968 | 3/20 | 0.54 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18716985 | 1.00 | MC4R (0.62) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18716918 | 1.00 | MC4R (0.62) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18716928 | 0.96 | MC4R (0.62) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18716884 | 0.96 | MC4R (0.62) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10089230 | 0.96 | MC4R (0.62) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18717067 | 0.95 | MC4R (0.64) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7865914 | 0.95 | MC4R (0.68) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18717060 | 0.95 | MC4R (0.64) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18717174 | 0.95 | MC4R (0.68) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18716852 | 0.95 | MC4R (0.68) | MC4RTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632171-B2 | Melanocortin receptor-specific peptides | PALATIN TECHNOLOGIES, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190216887-A1 | Melanocortin Receptor-Specific Peptides | PALATIN TECHNOLOGIES INC (US) | 2019-07-18 | — | — | US | disclosed |
| US-10179804-B2 | Melanocortin receptor-specific peptides | PALATIN TECHNOLOGIES, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| EP-2440572-B1 | LACTAM-BRIDGED MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20160318977-A1 | Melanocortin Receptor-Specific Peptides | PALATIN TECHNOLOGIES INC (US) | 2016-11-03 | — | — | US | disclosed |
| US-9458201-B2 | Melanocortin receptor-specific heptapeptides | PALATIN TECHNOLOGIES, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9273098-B2 | Lactam-bridged melanocortin receptor-specific peptides | PALATIN TECHNOLOGIES, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20140357575-A1 | Melanocortin Receptor-Specific Heptapeptides | PALATIN TECHNOLOGIES INC (US) | 2014-12-04 | — | — | US | disclosed |
| US-8846601-B2 | Melanocortin receptor-specific peptides | PALATIN TECHNOLOGIES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120178701-A1 | Melanocortin Receptor-Specific Peptides | PALATIN TECHNOLOGIES, INC. (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120077957-A1 | Lactam-Bridged Melanocortin Receptor-Specific Peptides | PALATIN TECHNOLOGIES, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2010144341-A2 | LACTAM-BRIDGED MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010144344-A2 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077957-A1 | Lactam-Bridged Melanocortin Receptor-Specific Peptides | MC1R, MC3R, MC4R | MC4R 3/4885TUBB4A 3074/4885TUBB 2518/4885 |
| US-10179804-B2 | Melanocortin receptor-specific peptides | MC1R, MC3R, MC5R | MC4R 4/4885TUBB4A 4677/4885TUBB 4534/4885 |
| US-20140357575-A1 | Melanocortin Receptor-Specific Heptapeptides | MC5R, MC1R, MC3R | MC4R 5/4885TUBB4A 4580/4885TUBB 4839/4885 |
| US-20190216887-A1 | Melanocortin Receptor-Specific Peptides | MC1R, MC3R, MC4R | MC4R 3/4885TUBB4A 4235/4885TUBB 4136/4885 |
| US-20160318977-A1 | Melanocortin Receptor-Specific Peptides | MC1R, MC3R, MC5R | MC4R 4/4885TUBB4A 4677/4885TUBB 4534/4885 |
| US-10632171-B2 | Melanocortin receptor-specific peptides | MC1R, MC3R, MC4R | MC4R 3/4885TUBB4A 4235/4885TUBB 4136/4885 |
| US-20120178701-A1 | Melanocortin Receptor-Specific Peptides | MC1R, MC3R, MC5R | MC4R 4/4885TUBB4A 4677/4885TUBB 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.