SCHEMBL7862469

SCHEMBL7862469

CSCC[C@H](NC(=O)c1ccc(CCC(=O)N(C2CCCCC2)C2CCCCC2)cc1-c1ccccc1C)C(=O)O.[LiH]

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.62
FNTB P49356 4/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6626154 0.99 FNTA (0.63) FNTAFNTB
SCHEMBL7870330 0.93 FNTA (0.61) FNTAFNTB
SCHEMBL6627108 0.92 FNTA (0.62) FNTAFNTB
Lithium Ion SCHEMBL7862467 0.92 FNTA (0.55) FNTAFNTB
SCHEMBL7869134 0.89 FNTA (0.69) FNTAFNTB
SCHEMBL6625720 0.88 FNTA (0.69) FNTAFNTB
SCHEMBL7870276 0.87 FNTA (0.62) FNTAFNTB
SCHEMBL7862503 0.87 FNTA (0.62) FNTAFNTB
SCHEMBL6627150 0.86 FNTA (0.63) FNTAFNTB
SCHEMBL6625203 0.86 FNTA (0.63) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 US disclosed