Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.65 |
| ▸ | FNTB | P49356 | 4/20 | 0.65 |
| ▸ | ICMT | O60725 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862495 | 1.00 | FNTA (0.65) | FNTAFNTBICMT | |
| SCHEMBL7869084 | 0.99 | FNTA (0.66) | FNTAFNTBICMT | |
| SCHEMBL7869081 | 0.99 | FNTA (0.66) | FNTAFNTBICMT | |
| SCHEMBL7862531 | 0.92 | FNTA (0.63) | FNTAFNTBICMT | |
| SCHEMBL7862534 | 0.92 | FNTA (0.63) | FNTAFNTBICMT | |
| SCHEMBL7871182 | 0.83 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL7870306 | 0.82 | FNTA (0.66) | FNTAFNTBICMT | |
| SCHEMBL7871180 | 0.82 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7870317 | 0.82 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL629257 | 0.81 | FNTA (0.69) | FNTAFNTBICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |