SCHEMBL7862767

SCHEMBL7862767

O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1CBr

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
CNR1 P21554 2/20 0.59
HRH1 P35367 1/20 0.55
HRH3 Q9Y5N1 1/20 0.55
SIGMAR1 Q99720 1/20 0.54
FAAH O00519 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3408891 0.83 HRH1 (0.64) POLBTDP1CNR1HRH1HRH3
SCHEMBL14524241 0.82 POLB (0.67) POLBTDP1CNR1HRH1HRH3
SCHEMBL7854933 0.82 POLB (0.62) POLBTDP1CNR1HRH1HRH3
SCHEMBL5333408 0.82 POLB (0.67) POLBTDP1CNR1HRH1HRH3
SCHEMBL15461433 0.81 CNR1 (0.80) POLBTDP1CNR1HRH1HRH3
SCHEMBL11885823 0.79 TDP1 (0.63) POLBTDP1CNR1HRH1HRH3
SCHEMBL11885815 0.79 POLB (0.63) POLBTDP1CNR1HRH1HRH3
SCHEMBL27815487 0.79 POLB (0.77) POLBTDP1MEN1KMT2A
SCHEMBL8203251 0.78 CNR1 (0.63) POLBTDP1CNR1HRH1HRH3
SCHEMBL2525261 0.78 CNR1 (0.73) POLBTDP1CNR1HRH1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900227-B1 IMPROVED PROCESS FOR THE SYNTHESIS OF DIESTERS OF PHOSPHORIC ACID 2,5-DIOXO-4,4-DIPHENYL-IMIDAZOLIDIN-1-YLMETHYL ESTER WARNER LAMBERT CO (US) 2001-12-12 EP disclosed
EP-0900227-B1 IMPROVED PROCESS FOR THE SYNTHESIS OF DIESTERS OF PHOSPHORIC ACID 2,5-DIOXO-4,4-DIPHENYL-IMIDAZOLIDIN-1-YLMETHYL ESTER WARNER LAMBERT CO (US) 2001-12-12 EP disclosed
US-6255492-B1 CHEMICAL INTERMEDIATES IN PRODUCTION OF 5,5-DIPHENYL-((3-PHOSPHONOOXY)METHYL)-2,4-IMIDAZOLIDINEDIONE DISODIUM SALT; USEFUL AS ANTICONVULSANT, ANTIEPILEPTIC, AND ANTIARRHYTHMIC AGENTS WARNER-LAMBERT COMPANY 2001-07-03 US disclosed
US-6255492-B1 CHEMICAL INTERMEDIATES IN PRODUCTION OF 5,5-DIPHENYL-((3-PHOSPHONOOXY)METHYL)-2,4-IMIDAZOLIDINEDIONE DISODIUM SALT; USEFUL AS ANTICONVULSANT, ANTIEPILEPTIC, AND ANTIARRHYTHMIC AGENTS WARNER-LAMBERT COMPANY 2001-07-03 US disclosed
US-6022975-A Process for the synthesis of diesters of phosphoric acid 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethyl ester WARNER-LAMBERT COMPANY (US) 2000-02-08 US disclosed
US-6022975-A Process for the synthesis of diesters of phosphoric acid 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethyl ester WARNER-LAMBERT COMPANY (US) 2000-02-08 US disclosed
EP-0900227-A1 IMPROVED PROCESS FOR THE SYNTHESIS OF DIESTERS OF PHOSPHORIC ACID 2,5-DIOXO-4,4-DIPHENYL-IMIDAZOLIDIN-1-YLMETHYL ESTER WARNER-LAMBERT COMPANY (US) 1999-03-10 EP disclosed
WO-1997041132-A1 IMPROVED PROCESS FOR THE SYNTHESIS OF DIESTERS OF PHOSPHORIC ACID 2,5-DIOXO-4,4-DIPHENYL-IMIDAZOLIDIN-1-YLMETHYL ESTER WARNER-LAMBERT COMPANY (US) 1997-11-06 WO disclosed