Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862712 | 1.00 | EGFR (0.51) | EGFRPPARABCL2L1MCL1CA12 | |
| SCHEMBL7867814 | 0.92 | MEN1 (0.48) | PPARABCL2L1MCL1CA12CA1 | |
| SCHEMBL7870448 | 0.91 | MAPT (0.48) | BCL2L1MCL1CA12CA1CA2 | |
| SCHEMBL7874606 | 0.91 | MAPT (0.48) | BCL2L1MCL1CA12CA1CA2 | |
| SCHEMBL7870554 | 0.91 | NPC1 (0.49) | PPARABCL2L1MCL1CA12CA1 | |
| SCHEMBL7869471 | 0.90 | KMT2A (0.54) | PPARACA12CA1CA2CA9 | |
| SCHEMBL7871673 | 0.89 | ACACB (0.43) | EGFRCA12CA1CA2CA9 | |
| SCHEMBL7870510 | 0.87 | CA1 (0.56) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL7874505 | 0.87 | EGFR (0.53) | EGFRPPARABCL2L1MCL1CA12 | |
| SCHEMBL7862777 | 0.87 | EGFR (0.53) | EGFRPPARABCL2L1MCL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |