Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.67 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.61 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.61 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744400 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL11326795 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL6163440 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL6163193 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL4722784 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL6164184 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL6161277 | 1.00 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL997383 | 0.98 | — | — | |
| SCHEMBL497606 | 0.90 | — | — | |
| SCHEMBL11322599 | 0.84 | EPHX2 (0.51) | EPHX1ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153029-A2 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000030688-A2 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2000-06-02 | — | — | WO | disclosed |