Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | MFN2 | O95140 | 1/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863046 | 1.00 | GBA1 (0.49) | GBA1SLC18A3MFN2FUCA1 | |
| SCHEMBL7863044 | 1.00 | GBA1 (0.49) | GBA1SLC18A3MFN2FUCA1 | |
| SCHEMBL7863048 | 1.00 | GBA1 (0.49) | GBA1SLC18A3MFN2FUCA1 | |
| SCHEMBL7863360 | 1.00 | GBA1 (0.49) | GBA1SLC18A3MFN2FUCA1 | |
| SCHEMBL27864969 | 0.82 | GBA1 (0.40) | GBA1 | |
| SCHEMBL5205480 | 0.81 | GBA1 (0.68) | GBA1SLC18A3 | |
| SCHEMBL6001919 | 0.81 | GBA1 (0.68) | GBA1SLC18A3 | |
| SCHEMBL5974321 | 0.81 | GBA1 (0.68) | GBA1SLC18A3 | |
| SCHEMBL5973809 | 0.81 | GBA1 (0.68) | GBA1SLC18A3 | |
| SCHEMBL6001914 | 0.81 | GBA1 (0.68) | GBA1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303593-B1 | FOR THERAPY HUMAN IMMUNODEFICIENCY VIRUS INFECTION, AQUIRED IMMUNODEFICIENCY SYNDROME (AIDS), INFLAMMATORY AND IMMUNOREGULATORY DISORDER OR DISEASE, ASTHMA, ALLERGIC RHINITIS, DERMATITIS, CONJUNCTIVITIS, ATHEROSCLEROSIS | MERCK & CO., INC. | 2001-10-16 | — | — | US | disclosed |