Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409455 | 0.90 | PDE10A (1.00) | PDE10A | |
| SCHEMBL410859 | 0.86 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7856900 | 0.83 | PDE10A (0.81) | PDE10AALDH1A1 | |
| SCHEMBL7808391 | 0.82 | PDE10A (0.86) | PDE10A | |
| SCHEMBL410399 | 0.82 | PDE10A (1.00) | PDE10A | |
| SCHEMBL411057 | 0.80 | PDE10A (1.00) | PDE10A | |
| SCHEMBL409914 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL410839 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL410931 | 0.77 | PDE10A (1.00) | PDE10A | |
| SCHEMBL409884 | 0.77 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138577-A1 | RADIOLABELED PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-12-02 | — | — | WO | disclosed |