Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129274 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9011790 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL841798 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19860394 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL54120 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8936938 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9083002 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL6047745 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21357398 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL989676 | 1.00 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483105-B2 | Solid drug-delivery devices employing fatty acid esters or fatty alcohol ethers of alkanediols as percutaneous absorption enhancers | ORTHO MCNEIL PHARM INC (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0272987-B1 | RESILIENT TRANSDERMAL DRUG-DELIVERY DEVICE AND COMPOSITIONS AND DEVICES EMPLOYING FATTY ACID ESTERS/ETHERS OR ALKANEDIOLS AS PERCUTANEOUS ABSORPTION ENHANCERS | CYGNUS THERAPEUTIC SYSTEMS (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0272918-B1 | DIFFUSION MATRIX FOR TRANSDERMAL DRUG ADMINISTRATION AND TRANSDERMAL DRUG DELIVERY DEVICES INCLUDING SAME | CYGNUS THERAPEUTIC SYSTEMS (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0483105-A1 | Solid drug-delivery devices employing fatty acid esters or fatty alcohol ethers of alkanediols as percutaneous absorption enhancers | CYGNUS THERAPEUTIC SYSTEMS (US) | 1992-04-29 | — | — | EP | disclosed |
| US-5006342-A | Resilient transdermal drug delivery device | CYGNUS CORPORATION (US) | 1991-04-09 | — | — | US | disclosed |
| US-4911916-A | Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same | CYGNUS RESEARCH CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4906463-A | Transdermal drug-delivery composition | CYGNUS RESEARCH CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0272918-A2 | Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same | CYGNUS THERAPEUTIC SYSTEMS (US) | 1988-06-29 | — | — | EP | disclosed |
| EP-0272987-A2 | Resilient transdermal drug-delivery device and compositions and devices employing fatty acid esters/ethers or alkanediols as percutaneous absorption enhancers | CYGNUS THERAPEUTIC SYSTEMS (US) | 1988-06-29 | — | — | EP | disclosed |