Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861361 | 1.00 | RARB (0.54) | RARBTDP1HRH3ALDH3A1DRD2 | |
| SCHEMBL7862607 | 0.98 | RARB (0.55) | RARBTDP1HRH3ALDH3A1DRD2 | |
| SCHEMBL13251235 | 0.92 | TDP1 (0.53) | RARBTDP1HRH3ALDH3A1DRD2 | |
| SCHEMBL16903841 | 0.86 | TDP1 (0.66) | TDP1DRD2DRD4DRD3KCNH2 | |
| SCHEMBL4025858 | 0.86 | HRH3 (0.46) | HRH3ALDH3A1DRD2DRD4DRD3 | |
| SCHEMBL30514014 | 0.84 | HRH3 (0.61) | HRH3ALDH3A1DRD2DRD4DRD3 | |
| SCHEMBL11815991 | 0.84 | HRH3 (0.61) | HRH3ALDH3A1DRD2DRD4DRD3 | |
| SCHEMBL7855892 | 0.83 | RARB (0.55) | RARBTDP1DRD2DRD4DRD3 | |
| SCHEMBL20021715 | 0.83 | TDP1 (0.56) | RARBTDP1 | |
| SCHEMBL12879356 | 0.82 | RARB (0.58) | RARBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623608-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0632031-B1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 2000-05-03 | — | — | EP | disclosed |
| EP-0546177-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5574061-A | ANTILIPEMIC AGENT, ANTIATHEROSCLEROSIS, ACAT INHIBITOR | TEIJIN LIMITED (JP) | 1996-11-12 | — | — | US | disclosed |
| US-5496853-A | FOR TREATING HYPERCHOLESTEROLEMIA | TEIJIN LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0632031-A1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0623608-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0546177-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |