Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834842 | 1.00 | TDP1 (0.43) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL1836223 | 1.00 | TDP1 (0.43) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL27160388 | 0.96 | TDP1 (0.40) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL11797179 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL1116213 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL1116257 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL9327276 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL5145681 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL3341694 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR | |
| SCHEMBL9173238 | 0.91 | TSHR (0.47) | TDP1FFAR1CPT2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129349-A | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2008-02-27 | — | — | CN | claimed |
| CN-101129349-A | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2008-02-27 | — | — | CN | disclosed |
| US-6303653-B1 | THERAPY OF HEPATOCYTE NUCLEAR FACTOR-4.ALPHA..SUP.1 (HNF-4) MEDIATED DISEASE BY ADMINISTERING CARBOXYLIC ACID OR ITS DERIVATIVE WHICH INHIBITS HNF-4 CONTROLLED TRANSCRIPTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-10-16 | — | — | US | disclosed |
| CN-1261274-A | carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2000-07-26 | — | — | CN | disclosed |
| EP-1001755-A2 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999000116-A2 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) | 1999-01-07 | — | — | WO | disclosed |