Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895830 | 0.80 | HDAC6 (0.74) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL12896097 | 0.79 | HDAC6 (0.69) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1264164 | 0.78 | HDAC6 (1.00) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1263374 | 0.77 | HDAC6 (0.71) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1264296 | 0.77 | HDAC6 (0.70) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL7864226 | 0.77 | HDAC6 (0.64) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1263779 | 0.77 | HDAC6 (0.66) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1264329 | 0.76 | HDAC6 (1.00) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1264520 | 0.76 | HDAC6 (1.00) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL1262773 | 0.76 | HDAC6 (0.64) | HDAC6HDAC8HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151318-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |