Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174303 | 0.83 | POLB (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10739512 | 0.83 | POLB (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL60588 | 0.83 | POLB (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31737192 | 0.83 | POLB (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10739509 | 0.83 | POLB (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14433706 | 0.83 | POLB (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15772906 | 0.80 | GRM4 (0.54) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12839883 | 0.80 | POLB (0.55) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| Bromide SCHEMBL7659080 | 0.80 | POLB (0.52) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28676184 | 0.80 | POLB (0.52) | POLBTDP1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316639-B1 | REACTING DICARBOXYLIC ACIDS OR ANHYDRIDES WITH A SALT OF HYDROXYL-AMINE IN SOLUTION SELECTED FROM HYDROXYLAMINE SULFATE, HYDROXYLAMINE NITRATE, HYDROXYLAMINE ACETATE, HYDROXYLAMINE TETRAFLUOROBORATE, HYDROXYLAMINE PHOSPHATE | Consortium für elektrochemische Industrie GmbH (DE) | 2001-11-13 | — | — | US | disclosed |